Alfa Aesar™ cis-4-Hydroxy-L-proline, 99%

Manufacturer: Alfa Aesar™ H2719403

Quantity 1g

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Catalog No. AAH2719403

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    Chemical Identifiers

    CAS 618-27-9
    Molecular Formula C5H9NO3
    Formula Weight 131.13g/mol
    MDL Number MFCD00064319
    Synonym (2S,4S)-(-)-4-Hydroxypyrrolidine-2-carboxylic acid; H-cis-Hyp-OH
    Chemical Name or Material cis-4-Hydroxy-L-proline

    Specifications

    Melting Point ≈250°C
    Quantity 1g
    Optical Rotation −59° (c=2 in Water)
    CAS 618-27-9
    Molecular Formula C5H9NO3
    Formula Weight 131.13g/mol
    MDL Number MFCD00064319
    Synonym (2S,4S)-(-)-4-Hydroxypyrrolidine-2-carboxylic acid; H-cis-Hyp-OH
    TSCA TSCA
    Chemical Name or Material cis-4-Hydroxy-L-proline
    Assay 99%

    Description

    Applications
    cis-4-Hydroxy-L-proline (CHP) is a proline analog that inhibits collagen synthesis and has been used as an anticancer compound. CHP blocked myotube formation and expression of sarcomeric myosin heavy chain in C2C12 murine skeletal muscle cells. CHP inhibited proliferation of murine Panc02 pancreatic carcinoma cell line3 and rat pancreatic carcinoma cell line DSL6A. cis-4-Hydroxy-L-proline and other hydrosyl-L-prolines are important intermediates for chiral synthesis of potential drugs.

    Solubility
    Soluble in water.

    Notes
    Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

    SDS & Safety Documents

  • Description & Specifications
  • Safety and Handling

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