Tocris™ CITCO

Selective CAR agonist

Manufacturer: Tocris™ 3683/10

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Catalog No. 36-831-0R

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For Research Use Only


    Specifications

    Product Type CITCO
    Inhibitors CITCO
    Purity >98
    Molecular Weight 436.74
    Quantity 10mg

    Constitutive androstane receptor (CAR) agonist (EC50 = 49nM). Displays > 100-fold selectivity over PXR receptors and no activity at LXR, ERα, ERβ, PPAR, RAR, FXR, VDR and THR. Induces CAR nuclear translocation and expression of CYP2B6 in hepatocytes in vitro.

    • Chemical Name: 6-(4-Chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde-O-(3,4-dichlorobenzyl)oxime
    • Formula: C19H12Cl3N3OS
    • CAS Number: 338404-52-7
    • Solubility: Soluble to 50mM in DMSO and to 5mM in ethanol
    • Purity: >98

  • Description & Specifications

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