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Clathrin light chain Antibody (CLC/1421), Alexa Fluor™ 532, Novus Biologicals™
SDP

Catalog No. NP24436A32 Shop All R&D Systems Products
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NP24436A32 0.1 mL
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Catalog No. NP24436A32 Supplier Novus Biologicals Supplier No. NBP254436AF532
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Description

Mouse Monoclonal Antibody

Clathrin light chain Monoclonal specifically detects Clathrin light chain in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Clathrin light chain
Applications Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone CLC/1421
Conjugate Alexa Fluor 532
Dilution Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias clathrin light chain A, clathrin, light chain A, LCA, light polypeptide (Lca)
Gene Symbols CLTA
Host Species Mouse
Immunogen Purified recombinant N-terminal fragment of human Clathrin Light Chain
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 1211
Test Specificity Recognizes proteins of 31-44kDa, which are identified as Clathrin Light Chains (both A B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60% homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG2b κ
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