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  6. CLEC10A/CD301 Antibody (ER-MP23) - BSA Free, Novus Biologicals™

CLEC10A/CD301 Antibody (ER-MP23) - BSA Free, Novus Biologicals™
SDP

Catalog No. NB10064874 Shop All R&D Systems Products
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0.125 mg
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NB10064874 0.125 mg
NB017659 0.025 mg
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Catalog No. NB10064874 Supplier Novus Biologicals Supplier No. NB10064874
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Description

Rat Monoclonal Antibody

CLEC10A/CD301 Monoclonal specifically detects CLEC10A/CD301 in Mouse samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen.

Specifications

Antigen CLEC10A/CD301
Applications Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone ER-MP23
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Alias CD301 antigen, CD301C-type lectin domain family 10 member A, CLECSF13, CLECSF14macrophage C-type lectin, C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 14 (macrophage-derived), C-type lectin domain family 10, member A, C-type lectin superfamily member 14, HML2, HMLC-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 13 (macrophage-derived), Macrophage lectin 2, macrophage lectin 2 (calcium dependent), MGL
Gene Symbols CLEC10A
Host Species Rat
Immunogen Balb/c macrophage precursor cell hybrids
Purification Method Protein G purified
Quantity 0.125 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Gene ID (Entrez) 10462
Test Specificity NB100-64874 recognizes murine CD301, a 38 kD cell surface protein that is otherwise known as macrophage galactose N-acetylgalactosamine lectin (MGL) or dendritic cell asialoglycoprotein (DC-ASGPR). In mice, CD301 is predominantly expressed on mature macrophages found associated with a wide range of connective tissues including macrophages in the dermis and the pancreas. Clone ER-MP23 also detects a population of dendritic cells in lymphoid tissue, which are probably recent immigrants from peripheral connective tissue sites. Expression of CD301 is induced by alternative (i.e. IL-4/IL-13 mediated) activation of macrophages and dendritic cells, but not all CD301 positive cells are necessarily IL-4/IL-13 stimulated. Clone ER-MP23 is reported to block the function of mouse CD301. The antibody binds both MGL1 and MGL2 homologues.
Target Species Mouse
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG2a
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