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Invitrogen™ COX1 Monoclonal Antibody (COX 111)
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Catalog No. 358100
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Catalog No. Quantity
35-810-0 100 μg
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Catalog No. 35-810-0 Supplier Invitrogen™ Supplier No. 358100
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Description

Mouse Monoclonal Antibody

COX1 Monoclonal Antibody for Western Blot, ICC/IF, IHC, Flow, ELISA

PTGS1 (COX1, Cyclooxygenase 1) is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen COX1
Applications ELISA, Flow Cytometry, Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone COX 111
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene PTGS1
Gene Accession No. O78749, P05979, P22437, P23219, Q63921
Gene Alias COI; COX1; Cox-1; COX3; Cox-3; COXI; cyclooxygenase 3; cyclooxygenase precursor (EC 1.14.99.1); cyclooxygenase-1; Cytochrome c oxidase polypeptide I; Cytochrome c oxidase subunit 1; cytochrome c oxidase subunit I; mitochondrially encoded cytochrome c oxidase I; Mtco1; mt-Co1; P PGG/HS; PCOX1; PES-1; PGG/HS; PGH synthase 1; PGHS1; Pghs-1; PHS 1; PHS1; prostaglandin endoperoxide synthase; prostaglandin G/H synthase 1; prostaglandin G/H synthase and cyclooxygenase; prostaglandin G/H synthase precursor (EC 1.14.99.1); prostaglandin H2 synthase 1; Prostaglandin-endoperoxide synthase 1; prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase); PTGHS; PTGS1; unnamed protein product
Gene Symbols COX1, PTGS1
Host Species Mouse
Immunogen Ram testes.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19224, 24693, 443551, 4512, 5742, 808251
Target Species Human, Mouse, Rat, Sheep
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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