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Tocris Bioscience™ CP 154526
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Catalog No. 277950
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Catalog No. Quantity
27-795-0 50 mg
27-791-0 10 mg
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Catalog No. 27-795-0 Supplier Tocris Bioscience™ Supplier No. 2779/50
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Description

Selective, non-peptide CRF1 antagonist

Selective, non-peptide CRF1 receptor antagonist (Ki values are 2.7 and > 10000 nM for CRF1 and CRF2 receptors respectively). Blocks CRF-induced adenylate cyclase activation (Ki = 3.7 nM) and attenuates activation of the HPA axis by CRF. Displays anxiolytic-like activity in the rat elevated plus-maze test; brain penetrant.

Chemical Identifiers

CAS 257639-98-8
Molecular Formula C23H33ClN4

Specifications

Quantity 50 mg
Formula Weight 400.99
Purity >99%
Molecular Weight (g/mol) 400.995
Chemical Name or Material CP 154526

Safety and Handling

Recommended Storage Desiccate at +4°C
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