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CRANAD 2, Tocris Bioscience™
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Catalog No. 480310
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Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Near-infrared probe that detects Aβ40 aggregates

Near-infrared probe that binds to Aβ40 aggregates (Kd = 38 nM) and elicits an emission blue shift. Shown to bind to plaques in APP-PS1 transgenic mice, in vitro. Detects senile plaques in 19-month-old Tg2576 mice in vivo. Penetrates the blood-brain barrier.

Chemical Identifiers

CAS 1193447-34-5
Molecular Formula C23H25BF2N2O2
Molecular Weight (g/mol) 410.272
InChI Key PVXQJYXODFZTBR-UHFFFAOYSA-N
Synonym t-4-1e,6e-1,7-bis 4-dimethylamino phenyl-1,6-heptadiene-3,5-dionato-ko3,ko5 difluoroboron
PubChem CID 90488972
IUPAC Name [4-[(2Z)-2-[6-[(E)-2-[4-(dimethylamino)phenyl]ethenyl]-2,2-difluoro-1,3-dioxa-2-boranuidacyclohex-5-en-4-ylidene]ethylidene]cyclohexa-2,5-dien-1-ylidene]-dimethylazanium
SMILES [B-]1(OC(=CC(=CC=C2C=CC(=[N+](C)C)C=C2)O1)C=CC3=CC=C(C=C3)N(C)C)(F)F

Specifications

Quantity 10 mg
Formula Weight 410.26
Percent Purity >98%
Chemical Name or Material CRANAD 2

Safety and Handling

Recommended Storage Store at -20°C
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