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Invitrogen™ CRBN Polyclonal Antibody
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Catalog No. PIPA598708
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100 μL
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PIPA598708 100 μL
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Catalog No. PIPA598708 Supplier Invitrogen™ Supplier No. PA598708
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Description

Rabbit Polyclonal Antibody

CRBN Polyclonal Antibody for ELISA, ICC/IF, IHC (P), Western Blot

CRBN, a member of the Lon protease protein family, plays a role in brain development. It is a component of the DCX (DDB1-CUL4-X-box) E3 protein ligase complex, a complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins and is required for limb outgrowth and expression of the fibroblast growth factor FGF8. CRBN is thought to regulate the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning via its interaction with KCNT1. It is widely expressed and highly expressed in brain.
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Specifications

Antigen CRBN
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.43 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene CRBN
Gene Accession No. Q8C7D2, Q96SW2
Gene Alias 2610203G15Rik; 2900045O07Rik; AD-006; AF229032; AW108261; cereblon; CRBN; DKFZp781K0715; MGC27358; MRT2; MRT2A; novel lethal; piL; protein cereblon; Protein PiL; protein x 0001
Gene Symbols CRBN
Host Species Rabbit
Immunogen Recombinant Human Protein cereblon protein (1-280AA).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51185, 58799
Target Species Human, Mouse
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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