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Cripto-1 TDGF1 Polyclonal Antibody, Rockland™
Rabbit Polyclonal Antibody
$174.73 - $636.24
Specifications
| Antigen | Cripto-1 TDGF1 |
|---|---|
| Concentration | 0.97 mg/mL |
| Applications | ELISA, Immunohistochemistry, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-199-1911
|
Rockland Immunochemicals
600401997 |
100 μg |
Each for $636.24
|
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50-199-1912
|
Rockland Immunochemicals
600401997S |
25 μL |
Each for $174.73
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Description
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This antibody is specific for human Cripto-1 protein. A BLAST analysis was used to suggest limited cross-reactivity with Cripto-1 from mouse based on a 70% homology with the immunizing sequence. Expect cross-reactivity with human Cripto-3 (TDGF2) based on very high levels of sequence conservation. Cross-reactivity with Cripto-1 from other sources has not been determined.
Cripto (TDGF1) is a GPI-anchored cell membrane proetin involved in Nodal signaling. Cell associated TDGF1 acts as a a Nodeal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulated Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells. TDGF1 is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers.Specifications
| Cripto-1 TDGF1 | |
| ELISA, Immunohistochemistry, Western Blot | |
| Unconjugated | |
| Rabbit | |
| Human | |
| P13385 | |
| 6997 | |
| Primary | |
| Antibody |
| 0.97 mg/mL | |
| Polyclonal | |
| Liquid | |
| RUO | |
| 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2 | |
| CR; CR1; CRGF; CRIPTO; cripto growth factor; Cripto-1; Cripto-1 growth factor; Cripto-3; epidermal growth factor-like Cripto protein; Epidermal growth factor-like cripto protein CR1; TDGF1; TDGF2; teratocarcinoma-derived growth factor; Teratocarcinoma-derived growth factor 1; TERATOCARCINOMA-DERIVED GROWTH FACTOR PRECURSOR (EPIDERMAL GROWTH FACTOR-LIKE CRIPTO PROTEIN) (CRIPTO GROWTH FACTOR) | |
| TDGF1 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| TDGF1 |
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