Invitrogen™ CSMD1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550645

Catalog No. PA550645

Description

The antibody detects endogenous levels of total CSMD1 protein.

CSMD1 CUB and Sushi multiple domains 1 is a protein that in humans is encoded by the CSMD1gene. It is a potential tumour suppressor, the deletion of which may result in head and neck carcinomas behaving more aggressively. CSMD1 is part of the complement system that defends against pathogens through either the classical pathway or the alternative pathway. Located primarily in nerve growth cones, CSMD1 blocks the classical pathway of the immune system and is thought to be involved in tumor suppression, as defects in the gene encoding CSMD1 are associated with squamous cell carcinomas.

Specifications

• Antigen: CSMD1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CSMD1
• Gene Alias: B930082H09; Csmd1; CUB and sushi domain-containing protein 1; CUB and Sushi multiple domains 1; CUB and sushi multiple domains protein 1; KIAA1890; Mdcr1; mKIAA1890; multiple domain complement regulator 1; PPP1R24; protein phosphatase 1, regulatory subunit 24; UNQ5952/PRO19863
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64478, 94109
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 3 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q923L3, Q96PZ7
• Gene Symbols: CSMD1
• Immunogen: Synthetic peptide corresponding to residues near the C terminal of human CUB and Sushi multiple domains 1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov