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CTLA-4 Antibody (1B8), Alexa Fluor™ 350, Novus Biologicals™
SDP

Catalog No. NP14100A350 Shop All R&D Systems Products
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NP14100A350 0.1 mL
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Catalog No. NP14100A350 Supplier Novus Biologicals Supplier No. NBP141000AF350
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Description

Armenian Hamster Monoclonal Antibody

CTLA-4 Monoclonal specifically detects CTLA-4 in Mouse samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence.

Specifications

Antigen CTLA-4
Applications Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Clone 1B8
Conjugate Alexa Fluor 350
Dilution Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias CD, CD152 antigen, CD152IDDM12, CD28, celiac disease 3, CELIAC3, CTLA-4, cytotoxic T-lymphocyte antigen 4, cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated protein 4, cytotoxic T-lymphocyte-associated serine esterase-4, GRD4, GSE, ICOS, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
Gene Symbols CTLA4
Host Species Armenian Hamster
Immunogen Extracellular portion of mouse CD152 fused to a mouse IgG2a.
Quantity 0.1 mL
Research Discipline Adaptive Immunity, Autoimmune Diseases, Cancer, Immune System Diseases, Immunology, Neuroscience, Signal Transduction
Primary or Secondary Primary
Gene ID (Entrez) 1493
Test Specificity This antibody recognises mouse CD152, commonly known as CTLA-4 (cytotoxic T-lymphocyte protein 4), a structural homolog for CD28. CD152 binds the same ligands as CD28, namely CD80 (B7.1) and CD86 (B7.2), but with much higher affinity. However, while binding of CD28 enhances T cell function, binding of CD152 inhibits it. CD152 is not detected on naive T-cells and is induced upon T-cell activation.
Target Species Mouse
Content And Storage Store at 4°C in the dark.
Isotype IgG
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