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CTLA-4 Antibody (1B8) - BSA Free, Novus Biologicals™
SDP

Catalog No. NBP14100001 Shop All R&D Systems Products
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0.1 mg
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NBP14100001 0.1 mg
NB018515 0.025 mg
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Catalog No. NBP14100001 Supplier Novus Biologicals Supplier No. NBP1410000.1MG
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Description

Armenian Hamster Monoclonal Antibody

CTLA-4 Monoclonal specifically detects CTLA-4 in Mouse samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunoprecipitation.

Specifications

Antigen CTLA-4
Applications Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
Classification Monoclonal
Clone 1B8
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:100, ELISA 1:100-1:2000, Immunocytochemistry/Immunofluorescence 1:10-1:2000, Immunoprecipitation 1:10-1:500
Formulation PBS (pH 7.4) with 0.09% Sodium Azide
Gene Accession No. P09793
Gene Alias CD, CD152 antigen, CD152IDDM12, CD28, celiac disease 3, CELIAC3, CTLA-4, cytotoxic T-lymphocyte antigen 4, cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated protein 4, cytotoxic T-lymphocyte-associated serine esterase-4, GRD4, GSE, ICOS, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
Gene Symbols CTLA4
Host Species Armenian Hamster
Immunogen Extracellular portion of mouse CD152 fused to a mouse IgG2a.
Purification Method Protein G purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Signal Transduction
Primary or Secondary Primary
Gene ID (Entrez) 1493
Test Specificity This antibody recognises mouse CD152, commonly known as CTLA-4 (cytotoxic T-lymphocyte protein 4), a structural homolog for CD28. CD152 binds the same ligands as CD28, namely CD80 (B7.1) and CD86 (B7.2), but with much higher affinity. However, while binding of CD28 enhances T cell function, binding of CD152 inhibits it. CD152 is not detected on naive T-cells and is induced upon T-cell activation.
Target Species Mouse
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG
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For Research Use Only

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