CTLA-4 Antibody (1B8), PE/Cy5.5, Novus Biologicals™

Armenian Hamster Monoclonal Antibody

Supplier:  Novus Biologicals NBP141000PECY55

Catalog No. N1410PECY55

Description

CTLA-4 Monoclonal specifically detects CTLA-4 in Mouse samples. It is validated for Flow Cytometry.

Specifications

• Antigen: CTLA-4
• Classification: Monoclonal
• Conjugate: PE-Cyanine5.5
• Formulation: PBS with 0.05% Sodium Azide
• Gene Symbols: CTLA4
• Immunogen: Extracellular portion of mouse CD152 fused to a mouse IgG2a.
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: This antibody recognises mouse CD152, commonly known as CTLA-4 (cytotoxic T-lymphocyte protein 4), a structural homolog for CD28. CD152 binds the same ligands as CD28, namely CD80 (B7.1) and CD86 (B7.2), but with much higher affinity. However, while binding of CD28 enhances T cell function, binding of CD152 inhibits it. CD152 is not detected on naive T-cells and is induced upon T-cell activation.
• Content And Storage: Store at 4°C in the dark. Do not freeze.

• Applications: Flow Cytometry
• Clone: 1B8
• Dilution: Flow Cytometry
• Gene Alias: CD, CD152 antigen, CD152IDDM12, CD28, celiac disease 3, CELIAC3, CTLA-4, cytotoxic T-lymphocyte antigen 4, cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated protein 4, cytotoxic T-lymphocyte-associated serine esterase-4, GRD4, GSE, ICOS, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
• Host Species: Armenian Hamster
• Purification Method: Protein G purified
• Research Discipline: Adaptive Immunity, Autoimmune Diseases, Cancer, Immune System Diseases, Immunology, Neuroscience, Signal Transduction
• Gene ID (Entrez): 1493.0
• Target Species: Mouse
• Isotype: IgG