Invitrogen™ CTU1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101194

Catalog No. PIPA5101194

Description

Antibody detects endogenous levels of total ATPBD3.

Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

Specifications

• Antigen: CTU1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CTU1
• Gene Alias: ATP binding domain 3; Atpbd3; ATP-binding domain-containing protein 3; BC005752; Cancer-associated gene protein; cancer-associated protein; CTU1; Cytoplasmic tRNA 2-thiolation protein 1; cytoplasmic tRNA adenylyltransferase 1; cytosolic thiouridylase subunit 1; cytosolic thiouridylase subunit 1 homolog; cytosolic thiouridylase subunit 1 homolog (S. pombe); NCS6
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 90353
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q7Z7A3
• Gene Symbols: CTU1
• Immunogen: A synthesized peptide derived from human CTU1(Accession Q7Z7A3), corresponding to amino acid residues L298-F348.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov