CUGBP2 Rabbit anti-Human, Mouse, Rat, Zebrafish, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-8346	Proteintech Group Inc 129211AP150UL	150 μL

Description

CUG-BP1 and CUG-BP2 are proteins that bind specifically to (CUG)8 oligonucleotides in vitro. While CUG-BP1 has the major binding activity in normal cells, nuclear CUG-BP2 binding activity increases in DM cells. Both CUG-BP1 and CUG-BP2 are isoforms of a novel heterogeneous nuclear ribonucleoprotein (hnRNP), hNab50. CUG-BP1, an RNA CUG triplet repeat binding protein, regulates splicing and translation of various RNAs. Expansion of RNA CUG repeats in the DMPK in DM is associated with alterations in binding activity of CUG-BP1 as well as alterations in the translation of the C/EBPb transcription factor. CUG-BP1 is an important regulator of initiation from different AUG codons of C/EBPb mRNA.

Specifications

• Antigen: CUGBP2
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat, Zebrafish
• Gene Accession No.: O95319, Q6P0B1, Q792H5, Q9Z0H4
• Gene ID (Entrez): 10659, 14007, 29428, 373117
• Immunogen: CUGBP2 Fusion Protein Ag3594
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: CELF2

• Concentration: 0.51 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: Bruno like protein 3, BRUNOL3, CELF 2, CELF2, CUG BP2, CUGBP2, ETR 3, ETR3, hNAPOR, NAPOR, RNA binding protein BRUNOL 3
• Gene Symbols: celf2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody