Cul2 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-157-2550	Bethyl Laboratories, Inc IHC00692T	10 μL
50-157-2549	Bethyl Laboratories, Inc IHC00692	100 μL

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Dog, Horse, Guinea pig_10141, Panda, Orangutan, Monkey, Gorilla, Chimpanzee,

CUL-2 is a member of the family of human cullin genes (CUL-1, -2, -3, -4a, -4b, and -5), homologous to the S. cerevisiae cdc53 gene. CUL-1 forms a complex with human p19skp1 and F box protein p45skp2. Together with cdc53 (Known as CulA), as three subunits, they form a ubiquitin ligase controlling proteolysis of G1 cell cycle regulatory proteins. In contrast to CUL-1, CUL-2 does not associate with p19skp1 and p45skp2. Instead, CUL-2 forms a complex with an inactive transcriptional elongation complex, SIII, formed by three subunits: Elongain C, Elongin B and VHL. The function of this association remains unknown.

Specifications

• Antigen: Cul2
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: CUL-2
• Immunogen: Between 150 and 200
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: CUL2

• Applications: Immunohistochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q13617, Q9D4H8
• Gene ID (Entrez): 71745, 8453
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody