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Cutaneous Lymphocyte Antigen Rat anti-Human, FITC, Clone: HECA-452, BD

Catalog No. p-7092717 Shop All BD Biosciences Products
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BDB555947 100 Tests
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Description

Rat Monoclonal Antibody

Reacts with cutaneous lymphocyte associated antigen (CLA), a carbohydrate domain shared by sialyl Lewis[x] (sLe[x]) and sialyl Lewis[a] (sLe[a]) antigens. It serves as the ligand for selectins including CD62E (ELAM-1) and CD62L (LECAM-1). CLA is expressed on lymphocytes in the skin on high endothelium. In peripheral blood, it is expressed on a small subset of lympocytes and all monocytes and granulocytes. It has been suggested that CLA plays a role in supporting lymphocyte migration to extravascular tissue during inflammation. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Mouse
Clone: HECA-452
Isotype: IgM, κ
Species Reactivity: Human

Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)

TRUSTED_SUSTAINABILITY

Specifications

Antigen Cutaneous Lymphocyte Antigen
Applications Flow Cytometry
Classification Monoclonal
Clone HECA-452
Conjugate FITC
Description CLA; PSGL-1; CD162; P-selectin glycoprotein ligand 1; SELPL; SELPLG
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Rat
Immunogen Lymphocyte-depleted Stromal Preparation of Tonsil
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human, Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgM κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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