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Tocris Bioscience™ CVT 313
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Catalog No. 617410
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Catalog No. Quantity
61-741-0 10 mg
61-745-0 50 mg
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Catalog No. 61-741-0 Supplier Tocris Bioscience™ Supplier No. 6174/10
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Description

cdk2 inhibitor

Cyclin-dependent kinase 2 (cdk2) inhibitor (reported IC50 values are 0.18 to 0.5 μM). Also inhibits cdk5 in sub-micromolar range (IC50 = 0.42 μM). Displays >7-fold selectivity for cdk2 and cdk5 over other cdks. Inhibits proliferation rat neonatal aortic smooth muscle cells and a range of tumor cells lines in vitro. Inhibits restenosis in a rat carotid artery injury model.

Chemical Identifiers

CAS 199986-75-9
Molecular Formula C20H28N6O3

Specifications

Quantity 10 mg
Solubility Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight 400.47
Physical Form Solid
Purity >98%
Molecular Weight (g/mol) 400.48
Chemical Name or Material 2,2'-[[6-[[(4-Methoxyphenyl)methyl]amino]-9-(1-methylethyl)-9H-purin-2-yl]imino]bis[ethanol]

Safety and Handling

Recommended Storage Store at -20°C
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