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  5. Tocris Bioscience™ CX08005

Tocris Bioscience™ CX08005
GREENER_CHOICE

Catalog No. 614425
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Competitive PTP1B inhibitor

CX08005 is a competitive PTP1B inhibitor (IC50 = 0.781 μM). Binds catalytic P-loop of enzyme. Improves insulin sensitivity in obese mice in the glucose tolerance test and the homeostasis model assessment of insulin resistance index (HOMA-IR) . Enhances insulin-induced glucose uptake in adipocytes and myotubes in vitro. Exhibits some selectivity for PTP1B over other protein tyrosine phosphatases, except TCPTP.

Specifications

Chemical Name or Material 2-[[[2-(Tetradecyl)phenyl]amino]carbonyl]benzoic acid
CAS 1256341-22-6
Quantity 25 mg
Molecular Formula C28H39N04
Purity 98%
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