CX3CR1 Rat anti-Human, PE, Clone: 2A9-1, BD

Rat Monoclonal Antibody

Manufacturer:  BD Biosciences 565798

Catalog No. BDB565798

Description

The 2A9-1 monoclonal antibody specifically binds to human CX3CR1, which is also known as chemokine (C-C) receptor-like 1 (CCRL1), Beta chemokine receptor-like 1 (CMK-BRL-1), G protein-coupled receptor 13 (GPR13), or GPRV28 (V28). CX3CR1 is a seven transmembrane G protein coupled receptor that is expressed by NK cells, T cells, and monocytes. The cellular expression of CX3CR1 is correlated with high levels of intracellular perforin and granzyme B. CX3CR1 serves as a receptor for fractalkine (CX3CL1). Fractalkine is a transmembrane chemokine of the CX3C family that is expressed on activated endothelial cells, neurons, and astrocytes. Interaction of CX3CR1 with fractalkine initiates cellular adhesive and chemotactic responses.

Specifications

• Antigen: CX3CR1
• Clone: 2A9-1
• Description: CCRL1; CMKBRL1; CMKDR1; GPR13; GPRV28; V28; Fractalkine Receptor
• Format: Affinity Purified
• Immunogen: Human CX3CR1 Recombinant Protein
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human

• Applications: Flow Cytometry
• Conjugate: PE
• Formulation: Aqueous buffered solution containing BSA and ≤0.2% sodium azide.
• Host Species: Rat
• Isotype: IgG_2b, κ
• Quantity: 25 Tests
• Storage Requirements: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
• Monoclonal or Polyclonal: Monoclonal

For Research Use Only.