Invitrogen™ CXCL14 Polyclonal Antibody, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ 500P237100UG

Catalog No. 500P237100

Description

AA Sequence of recombinant protein: SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIITTKS VSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human BRAK (CXCL14). Anti-Human BRAK (CXCL14)-specific antibody was purified by affinity chromatography employing an immobilized Human BRAK (CXCL14) matrix. Sandwich ELISA: To detect Human BRAK (CXCL14) by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human BRAK (CXCL14) (500-P237Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human BRAK (CXCL14). Western Blot: To detect Human BRAK (CXCL14) by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human BRAK (CXCL14) is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

This gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation.

Specifications

• Antigen: CXCL14
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cxcl14
• Gene Alias: 1110031L23Rik; 1200006I23Rik; AI414372; B-cell and monocyte-activating chemokine; BMAC; bolekine; BRAK; breast and kidney; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 14; chemokine BRAK; CXC; CXC chemokine in breast and kidney; CXC motif chemokine; C-X-C motif chemokine 14; C-X-C motif chemokine ligand 14; CXCL; Cxcl14; hypothetical protein LOC511771; Kec; Kidney-expressed chemokine CXC; KS1; MGC10687; MIP-2 gamma; MIP2G; MIP-2g; MIP2gamma; musculus CXC chemokine MIP-2gamma; NJAC; PSEC0212; SCYB14; small inducible cytokine B14; small inducible cytokine subfamily B (Cys-X-Cys), member 14; small inducible cytokine subfamily B (Cys-X-Cys), member 14 (BRAK); small-inducible cytokine B14; tumor-suppressing chemokine; UNQ240/PRO273
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9547
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Western Blot
• Concentration: 0.1-1.0 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: O95715
• Gene Symbols: Cxcl14
• Immunogen: E.coli-derived Recombinant Human BRAK (CXCL14).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody