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Invitrogen™ CYP1B1 Recombinant Rabbit Monoclonal Antibody (K01_1Q09)
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Catalog No. MA563709
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MA563709 100 μL
MA565168 50 μL
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: NHDPLKWPNP ENFDPARFLD KDGLINKDLT SRVMIFSVGK RRCIGEELSK MQLFLFISIL AHQCDFRANP NEPAKMNFSY GLTIKPKSFK VNVTLRESME LLDSAVQNLQ AKETCQ Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 79%, Pig - 84%, Cynomolgus monkey - 94%.

CYP1B1 is a 543 amino acid intracellular protein localized to the endoplasmic reticulum. It belongs to the cytochrome P450 super family of enzymes which are monooxygenases and it catalyzes many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol and is also involved in the metabolism of substances active in the eye growth and differentiation and hence plays a putative role in ocular development. Mutated proteins are known to cause primary congenital glaucoma.
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Specifications

Antigen CYP1B1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone K01_1Q09
Concentration 1.30 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 40% glycerol, 0.05% BSA, 150mM NaCl and 0.01% sodium azide; pH 7.4
Gene Cyp1b1
Gene Accession No. Q16678, Q64678
Gene Alias aryl hydrocarbon hydroxylase; benz[a]anthracene inducible; CP1B; CYP1B; CYP1B1; Cyp1-b1; CYPIB1; cytochrome P450 1B; cytochrome P450 1B1; cytochrome P450 family 1 subfamily B member 1; cytochrome P450, 1b1, benz[a]anthracene inducible; cytochrome P450, family 1, subfamily B, polypeptide 1; cytochrome P450, subfamily 1B, polypeptide 1; cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile); cytochrome P4501B; cytochrome P450CMEF; Cytochrome P450EF; cytochrome P450RAP; flavoprotein-linked monooxygenase; GLC3A; Hydroperoxy icosatetraenoate dehydratase; microsomal monooxygenase; P4501B1; P450RAP; xenobiotic monooxygenase; zgc:136223
Gene Symbols Cyp1b1
Host Species Rabbit
Immunogen Recombinant protein of human CYP1B1 (aa 428-543).
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1545, 25426
Target Species Human, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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