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  6. Invitrogen™ Cytochrome C Monoclonal Antibody (6H2), eBioscience™ 

Invitrogen™ Cytochrome C Monoclonal Antibody (6H2), eBioscience™
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Catalog No. 5013491
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100 μg
2 mg
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Catalog No. Quantity
50-134-91 100 μg
14-660-137 2 mg
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Catalog No. 50-134-91 Supplier Invitrogen™ Supplier No. 14660182
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Description

Mouse Monoclonal Antibody

Description: The 6H2 antibody reacts with the native form of mouse, human, and rat cytochrome c. Applications Reported: The 6H2 antibody has been reported for use in intracellular flow cytometric analysis, and immunoprecipitation. (Fluorochrome conjugated 6H2 is recommended for use in intracellular flow cytometry.). Applications Tested: The 6H2 antibody has been tested by intracellular flow cytometric analysis. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.

Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP. Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli. In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytochrome C
Applications Flow Cytometry, Immunoprecipitation
Classification Monoclonal
Clone 6H2
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene Cycs
Gene Accession No. P62897, P62898, P99999
Gene Alias CG17903; CG17903-PA; CG17903-PB; CRF; CYC; CYC2; Cycs; CYCSA; Cyct-c-p; Cyt c; cyt c-p; cyt.c; CytC; Cyt-c; CYTC2; Cyt-c2; CytC-2; cyt-c-p; cytC-p; Cyt-c-p-PA; Cyt-c-p-PB; Cytochrome c; cytochrome c DC4; Cytochrome c proximal; Cytochrome C, expressed in somatic tissues; cytochrome c, somatic; Cytochrome c-2; cytochrome c-like; cytochrome c-like protein; Cytochrome c-proximal; cytochrome-c-p; Cytochrome-c-proximal; DC4; dCyt.C-p; DMc01; Dmel\CG17903; Dmel_CG17903; hc1; HCS; l(2)k13905; lethal (2) k13905; LOC100341175; LOC100357840; MGC128356 protein; pDMc01; RH17228p; THC4
Gene Symbols Cycs
Host Species Mouse
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13063, 25309, 54205
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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