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Cytokeratin 18 Antibody (Cocktail) - IHC-Prediluted, Novus Biologicals™
SDP

Catalog No. NBP248076 Shop All R&D Systems Products
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NBP248076 7 mL
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Catalog No. NBP248076 Supplier Novus Biologicals Supplier No. NBP248076
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Description

Mouse Monoclonal Antibody

Cytokeratin 18 Monoclonal specifically detects Cytokeratin 18 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Cytokeratin 18
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone Cocktail
Conjugate Unconjugated
Dilution Immunohistochemistry-Paraffin
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias Cell proliferation-inducing gene 46 protein, cell proliferation-inducing protein 46, CK-18, CYK18, cytokeratin 18, cytokeratin-18, K18, keratin 18, keratin, type I cytoskeletal 18, keratin-18
Gene Symbols KRT18
Host Species Mouse
Immunogen Recombinant full-length human Cytokeratin 18 protein (Uniprot: P05783)
Molecular Weight of Antigen 45 kDa
Purification Method Protein A or G purified
Quantity 7 mL
Regulatory Status RUO
Research Discipline Cancer, Cell Biology, Cellular Markers, Cytoskeleton Markers
Primary or Secondary Primary
Gene ID (Entrez) 3875
Test Specificity This monoclonal antibody reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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