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Cytokeratin 18 Antibody (KRT18/834) - Azide and BSA Free, Novus Biologicals™
SDP

Catalog No. NBP247985B Shop All R&D Systems Products
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NBP247985B 0.2 mg
NBP247985A 0.1 mg
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Catalog No. NBP247985B Supplier Novus Biologicals Supplier No. NBP2479850.2MG

Mouse Monoclonal Antibody

Cytokeratin 18 Monoclonal antibody specifically detects Antigen in Bovine (Negative), Canine (Negative), Hamster (Negative), Human, Mouse (Negative), Porcine (Negative), Rat (Negative), Sheep (Negative) samples. It is validated for Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin).

Specifications

Antigen Cytokeratin 18
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
Classification Monoclonal
Clone KRT18/834
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready
Formulation PBS with No Preservative
Gene Alias Cell proliferation-inducing gene 46 protein, cell proliferation-inducing protein 46, CK-18, CYK18, cytokeratin 18, cytokeratin-18, K18, keratin 18, keratin, type I cytoskeletal 18, keratin-18
Gene Symbols KRT18
Host Species Mouse
Immunogen Recombinant full-length human KRT18 protein
Molecular Weight of Antigen 45 kDa
Purification Method Protein A or G purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Cancer, Cell Biology, Cellular Markers, Cytoskeleton Markers
Primary or Secondary Primary
Gene ID (Entrez) 3875
Test Specificity This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
Target Species Human, Bovine (Negative), Canine (Negative), Hamster (Negative), Mouse (Negative), Porcine (Negative), Rat (Negative)
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG1
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