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Cytokeratin 5/14 Antibody (XM26/LL002), Novus Biologicals™
SDP

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NB11059922 6 mL
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Catalog No. NB11059922 Supplier Novus Biologicals Supplier No. NB11059922
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Description

Mouse Monoclonal Antibody has been used in 2 publications

Cytokeratin 5/14 Monoclonal specifically detects Cytokeratin 5/14 in Human samples. It is validated for Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

Antigen Cytokeratin 5/14
Applications Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone XM26/LL002
Conjugate Unconjugated
Dilution Immunohistochemistry 1:25-1:75, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:25-1:75
Gene Alias 58 kDa cytokeratin, CK5, CK-5, cytokeratin-5, DDD, EBS2, epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types, K5, keratin 5, keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockaynetypes), keratin, type II cytoskeletal 5, Keratin-5, KRT5A, Type-II keratin Kb5
Gene Symbols KRT5
Host Species Mouse
Immunogen XM26: prokaryotic recombinant protein corresponding to 103 amino acid portion of C-terminal region of the human cytokeratin 5 molecule. LL002: Synthetic peptide of the extreme c-terminal of human keratin-14
Purification Method Protein A or G purified
Quantity 6 mL
Regulatory Status RUO
Research Discipline Cytoskeleton Markers
Primary or Secondary Primary
Gene ID (Entrez) 3852
Test Specificity This antibody cocktail reacts with cytokeratin 5 intermediate filament protein as well as to 50 kD cytokeratin protein designated cytokeratin 14. Basal cells of human epidermis express acidic cytokeratin 14 and basic cytokeratin 5. Cytokeratin 5 is a 58 kD protein which is closely related to cytokeratin 6. Cytokeratin 5 and 6 are expressed in basal cell epithelioma, basal cells of prostate, urothelium, vagina, squamous cell carcinomas of skin, tongue, epiglottis, and in the rectal-anal region. Cytokeratin 5 can be useful in the destinction of mesotheliomas from most adenocarcinomas. Cytokeratin 14 belongs to the type A (acidic) subfamily of low MW cytokeratins and exists in combination with cytokeratin 15. This antibody can be useful to distinguish stratified ephithelial cells from simple epithelial cells.
Target Species Human
Content And Storage Store at 4°C.
Form Purified
Isotype IgG1, IgG3
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For Research Use Only

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