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Cytokeratin, Acidic (Type I or LMW) Antibody (SPM115), Alexa Fluor™ 647, Novus Biologicals™
SDP

Catalog No. NBP234393Y Shop All R&D Systems Products
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Catalog No. NBP234393Y Supplier Novus Biologicals Supplier No. NBP234393AF647
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Description

Mouse Monoclonal Antibody

Cytokeratin, Acidic (Type I or LMW) Monoclonal specifically detects Cytokeratin, Acidic (Type I or LMW) in Human, Mouse, Rat, Bovine, Canine, Chicken, Monkey, Rabbit, Reptile samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

Antigen Cytokeratin, Acidic (Type I or LMW)
Applications Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone SPM115
Conjugate Alexa Fluor 647
Dilution Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias CK10, CK14, CK15, CK16, CK19, cytokeratin 10, cytokeratin 14, cytokeratin 15, cytokeratin 16, cytokeratin 19
Host Species Mouse
Immunogen Human epidermal keratin (Uniprot: Q7Z794)
Molecular Weight of Antigen 49 kDa
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity This monoclonal antibody recognizes the 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40kDa. monoclonal antibody SPM116 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. SPM115/SPM116 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
Target Species Human, Mouse, Rat, Bovine, Canine, Chicken, Primate, Rabbit, Reptile
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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