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Cytokeratin, Basic (Type II or HMW) Antibody (SPM116), PE, Novus Biologicals™
SDP

Catalog No. NBP234395PE Shop All R&D Systems Products
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Catalog No. NBP234395PE Supplier Novus Biologicals Supplier No. NBP234395PE
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Description

Mouse Monoclonal Antibody

Cytokeratin, Basic (Type II or HMW) Monoclonal specifically detects Cytokeratin, Basic (Type II or HMW) in Human, Mouse, Rat, Bovine, Canine, Chicken, Monkey, Rabbit samples. It is validated for Flow Cytometry.

Specifications

Antigen Cytokeratin, Basic (Type II or HMW)
Applications Flow Cytometry
Classification Monoclonal
Clone SPM116
Conjugate PE
Dilution Flow Cytometry
Gene Alias CK1, CK10, CK14, CK5, cytokeratin 1, cytokeratin 10, cytokeratin 14, cytokeratin 5
Host Species Mouse
Immunogen Human epidermal keratin (Uniprot: Q01546)
Molecular Weight of Antigen 59 kDa
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity This monoclonal antibody recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40kDa. This monoclonal antibody recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. SPM115/SPM116 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
Target Species Human, Mouse, Rat, Bovine, Canine, Chicken, Primate, Rabbit
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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