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D2HGDH Mouse anti-Human, Mouse, Clone: 1E9B3, Proteintech
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Catalog No. 501736794 Shop All Proteintech Group Inc Products
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50-173-6794 150 μL
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Catalog No. 50-173-6794 Supplier Proteintech Group Inc Supplier No. 663641IG150UL
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Mouse Monoclonal Antibody

This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.

Specifications

Antigen D2HGDH
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1E9B3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene D2HGDH
Gene Accession No. Q8CIM3, Q8N465
Gene Alias D2HGD, D2HGDH
Gene Symbols D2HGDH
Host Species Mouse
Immunogen D2HGDH Fusion Protein Ag5036
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 728294, 98314
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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