DAAM2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-4786	Proteintech Group Inc 252061AP150UL	150 μL

Description

DAAM2 is a recently identified planar cell polarity (PCP) signaling molecule implicated in the regulation of cellular polarity, convergent extension, and invasion. DAAM2 belongs to the formin homology family and contains a DAD (diaphanous autoregulatory) domain, an FH1 (formin homology 1) domain, an FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/ formin homology 3) domain. The DAAM2 protein is known to be involved in cell divison. Though the exact function of DAAM2 is yet unknown, reports suggest that it is closely related to DAAM1 and hence along with DAAM1 it may also be required in Wnt/Fz signaling and activation of Rho and in regulating cytoskeleton architecture. DAAM2 is expressed in most of tissues but the expression level ishigher in brain.

Specifications

• Antigen: DAAM2
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: Q80U19, Q86T65
• Gene ID (Entrez): 23500, 316201, 76441
• Immunogen: DAAM2 Fusion Protein Ag18955
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: DAAM2

• Concentration: 0.34 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: DAAM2, KIAA0381
• Gene Symbols: Daam2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody