Tocris™ DBM 1285 dihydrochloride

p38 MAPK inhibitor; anti-inflammatory

Manufacturer: Tocris™ 5095/10

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Catalog No. 50-951-0R

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For Research Use Only


    Inhibitors DBM 1285 dihydrochloride
    Purity >98
    Molecular Weight 468.42
    Quantity 10mg
    Product Type DBM 1285 dihydrochloride

    p38 MAPK inhibitor. Supresses p38 phosphorylation and LPS-induced TNF-α production in macrophages and in vivo. Attenuates zymosan-induced inflammation and adjuvant-induced arthritis in murine models. Orally active.

    • Chemical Name: N-Cyclopropyl-4-[4-(4-fluorophenyl)-2-(4-piperidinyl)-5-thiazolyl]-2-pyrimidinamine dihydrochloride
    • Formula: C21H22FN5S.2HCl
    • Solubility: Soluble to 100mM in water
    • Purity: >98

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