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Invitrogen™ DDX3 Polyclonal Antibody
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Catalog No. PIPA520224
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100 μg
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Catalog No. Quantity
PIPA520224 100 μg
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Catalog No. PIPA520224 Supplier Invitrogen™ Supplier No. PA520224
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Description

Rabbit Polyclonal Antibody

A suggested positive control is HepG2 cell lysate. PA5-20224 can be used with blocking peptide PEP-0337.

The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DDX3
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene DDX3X
Gene Accession No. O00571, Q62167
Gene Alias ATP-dependent RNA helicase DDX3X; CAP-Rf; D1Pas1-related sequence 2; D1Pas1-rs2; DBX; DDX14; DDX3; Ddx3x; D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 3; DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 3; DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked; DEAD box protein 3, X-chromosomal; DEAD box RNA helicase DEAD3; DEAD box, X isoform; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked; DEAD/H box-3; Dead3; DEAD-box helicase 3, X-linked; DEAD-box protein 3 (DEAD-box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1PAS1 related sequence 2); Embryonic RNA helicase; Erh; fibroblast growth factor inducible 14; Fin14; Helicase-like protein 2; HLP2; mDEAD3; MRX102
Gene Symbols DDX3X
Host Species Rabbit
Immunogen A 16 amino acid peptide from near the amino terminus of human DDX3.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13205, 1654
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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