DDX41 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-155-9117	Bethyl Laboratories, Inc A301050AT	20 μL

Description

The recommended shelf life for this product is 1 year from date of receipt.

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. DDX41, also known as Abstrakt, interacts with and regulates the expression of sorting nexin-2 (SNX2), a protein involved in protein sorting in the trans-Golgi network. Recent evidence suggests that DDX41 also plays a role in the innate immune response by sensing intracellular viral DNA, triggering TBK1 and IRF3 activation, leading to a type I interferon immune response.

Specifications

• Antigen: DDX41
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: ABS, 2900024F02Rik, DEAD box protein 41, DEAD box protein abstrakt homolog, DEAD-box protein abstrakt, probable ATP-dependent RNA helicase DDX41, putative RNA helicase
• Immunogen: Between 572 and C-term
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: DDX41

• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q91VN6, Q9UJV9
• Gene ID (Entrez): 51428, 72935
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody