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DDX41 Polyclonal Antibody, Bethyl Laboratories

Catalog No. p-7140606
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Catalog No. Quantity
50-155-9117 20 μL
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Catalog No. 50-155-9117 Supplier Bethyl Laboratories, Inc Supplier No. A301050AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. DDX41, also known as Abstrakt, interacts with and regulates the expression of sorting nexin-2 (SNX2), a protein involved in protein sorting in the trans-Golgi network. Recent evidence suggests that DDX41 also plays a role in the innate immune response by sensing intracellular viral DNA, triggering TBK1 and IRF3 activation, leading to a type I interferon immune response.

Specifications

Antigen DDX41
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene DDX41
Gene Accession No. Q91VN6, Q9UJV9
Gene Alias ABS, 2900024F02Rik, DEAD box protein 41, DEAD box protein abstrakt homolog, DEAD-box protein abstrakt, probable ATP-dependent RNA helicase DDX41, putative RNA helicase
Gene Symbols DDX41
Host Species Rabbit
Immunogen Between 572 and C-term
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51428, 72935
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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