DENND1A Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-5009	Proteintech Group Inc 256581AP150UL	150 μL

Description

This antibody (25658-1-AP) can recognize all isoforms at 112 kDa and 52-64 kDa.

Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2). Thus, connecdenns link RAB35 activation with the clathrin machinery.

Specifications

• Antigen: DENND1A
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: Q8TEH3
• Gene ID (Entrez): 57706
• Immunogen: DENND1A Fusion Protein Ag22547
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: DENND1A

• Concentration: 0.31 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: Connecdenn, DENN/MADD domain containing 1A, DENND1A, FAM31A, KIAA1608, Protein FAM31A, RP11 230L22.3
• Gene Symbols: DENND1A
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody