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Desmin Antibody (DES/1711), Alexa Fluor™ 750, Novus Biologicals™
SDP

Catalog No. NP2403A70 Shop All R&D Systems Products
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NP2403A70 0.1 mL
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Catalog No. NP2403A70 Supplier Novus Biologicals Supplier No. NBP254503AF750
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Description

Mouse Monoclonal Antibody

Desmin Monoclonal specifically detects Desmin in Human, Mouse, Rat, Chicken, Hamster samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

Antigen Desmin
Applications Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone DES/1711
Conjugate Alexa Fluor 750
Dilution Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias CMD1IFLJ41013, CSM1, CSM2, desmin, FLJ12025, FLJ39719, FLJ41793, intermediate filament protein
Gene Symbols DES
Host Species Mouse
Immunogen Recombinant human desmin protein (Uniprot: P17661)
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 1674
Test Specificity Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain -helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.
Target Species Human, Mouse, Rat, Chicken, Hamster
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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