DFNA5 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-8469	150 μL

Catalog No. 50-172-8469 Supplier Proteintech Group Inc Supplier No. 130751AP150UL

Description

Rabbit Polyclonal Antibody

DFNA5 (deafness, autosomal domit 5), also known as ICERE-1, is a 496 amino acid protein that is expressed in cochlea tissue, as well as in placenta, brain, heart, liver, lung and pancreas as two alternatively spliced isoforms, designated short and long. Defects in the gene encoding DFNA5 are the cause of non-syndromic sensorineural deafness autosomal domit type 5 (DFNA5), a form of sensorineural hearing loss that results from damage to one of various structures that receive sound information in the brain. The gene encoding DFNA5 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Specifications

• Antigen: DFNA5
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.3 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: DFNA5
• Gene Accession No.: O60443, Q9Z2D3
• Gene Alias: deafness, autosomal domit 5, DFNA5, GSDME, ICERE 1, ICERE1
• Gene Symbols: DFNA5
• Host Species: Rabbit
• Immunogen: DFNA5 Fusion Protein Ag3746
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1687, 54722
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG