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Invitrogen™ DNAJC13 Polyclonal Antibody
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Catalog No. PIPA538026
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Quantity:
100 μg
Catalog No. Quantity
PIPA538026 100 μg
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Catalog No. PIPA538026

Supplier: Invitrogen™ PA538026

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Description

Rabbit Polyclonal Antibody

A recommended positive control is human heart tissue lysate. At least two isoforms of DNAJC13 are known to exist; this antibody will detect both isoforms. DNAJC13 antibody is not expected to cross-react with other DNAJC family members.

DNAJC13, also known as receptor-mediated endocytosis 8 (RME8), is the human homolog to a DnaJ domain-containing protein originally identified in a screen for endocytic defects in C. elegans. It is thought to be a co-chaperone of Hsc70 which regulates protein conformation at membrane sites and plays a role in intracellular trafficking, co-localizing with markers of the endosomal system. Recent experiments have indicated that the DNAJC13 protein is involved in membrane trafficking through early endosomes but not through degradative organelles. DNAJC13 has been also been shown to regulate the intracellular trafficking of the epidermal growth factor receptor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DNAJC13
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene DNAJC13
Gene Accession No. O75165
Gene Alias D030002L11Rik; DnaJ (Hsp40) homolog, subfamily C, member 13; DnaJ domain-containing protein RME-8; DnaJ heat shock protein family (Hsp40) member C13; dnaJ homolog subfamily C member 13; DNAJC13; Gm1124; j-domain containing protein, required for endocytosis; KIAA0678; mKIAA0678; PARK21; receptor mediated endocytosis RME-8; required for receptor-mediated endocytosis 8; Rme8; RME-8
Gene Symbols DNAJC13
Host Species Rabbit
Immunogen 18 amino acid peptide near the carboxy terminus of human DNAJC13.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23317, 235567
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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