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Invitrogen™ DOCK4 Polyclonal Antibody
Rabbit Polyclonal Antibody
$209.50 - $511.50
Specifications
| Antigen | DOCK4 |
|---|---|
| Concentration | 0.5 mg/mL |
| Content And Storage | -20°C |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|
PIPA5119079
|
Invitrogen™
PA5119079 |
200 μL |
Each for $511.50
|
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PIPA5122029
|
Invitrogen™
PA5122029 |
20 μL |
Each for $209.50
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Description
DOCK4 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)
The DOCK4 gene encodes the dedicator of cytokinesis 4 protein, a member of the DOCK family, which functions as a guanine nucleotide exchange factor (GEF) for small Rho GTPases, specifically Rac1 and Rap1. DOCK4 is critical for regulating various cellular processes, including cell migration, polarity, and cytoskeletal organization. It plays a significant role in maintaining the integrity of endothelial barriers and mediating intercellular junctions. Mutations or altered expression of DOCK4 have been implicated in cancer progression, particularly in tumor metastasis and invasion, by affecting the adhesion and migration of cancer cells. Additionally, DOCK4 is involved in neurodevelopmental processes and has been associated with psychiatric disorders, reflecting its importance in brain function and development. Understanding the roles of DOCK4 in both health and disease could provide insights into therapeutic strategies for cancer and neurological disorders where these pathways are disrupted.Specifications
| DOCK4 | |
| -20°C | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human | |
| DOCK4 | |
| 5330406C03; 6330411N01Rik; AF263288; C030023J22; dedicator of cytokinesis 4; dedicator of cytokinesis protein 4; DOCK4; Kiaa0716; mKIAA0716; RGD1561724 | |
| DOCK4 | |
| Primary | |
| Antigen affinity chromatography |
| 0.5 mg/mL | |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 50% glycerol and 0.05% ProClin 300 | |
| Q8N1I0 | |
| 9732 | |
| Recombinant protein Dedicator Of Cytokinesis 4. The antigen corresponds to amino acid range 1-300 of the target protein. | |
| Antibody |
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