Invitrogen™ DPF1 Polyclonal Antibody

Catalog No.	Quantity
PIPA561895	100 μL

Catalog No. PIPA561895

Supplier: Invitrogen™ PA561895

Description

Rabbit Polyclonal Antibody

Immunogen sequence: VLEALLCAET GEKKIELKEE ETIMDCQKQQ LLEFPHDLEV EDLEDDIPRR KNRAKGKAYG IGGLRKRQDT ASLEDR Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.

Specifications

• Antigen: DPF1
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: DPF1
• Gene Accession No.: Q92782
• Gene Alias: Baf45b; BRG1-associated factor 45B; D4, zinc and double PHD fingers family 1; double PHD fingers 1; DPF1; NEU BAF45b; NEUD4; neuro-d4; neuro-d4 homolog; neuronal d4 domain family member; zinc finger protein neuro-d4
• Gene Symbols: DPF1
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human DPF1. Recombinant protein control fragment (Product #RP-101097).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8193
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG