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Invitrogen™ DPF1 Polyclonal Antibody
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Catalog No. PIPA540878
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100 μL
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PIPA540878 100 μL
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Catalog No. PIPA540878 Supplier Invitrogen™ Supplier No. PA540878
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Description

Rabbit Polyclonal Antibody

Peptide sequence: KELAWVPEAQ RKHTAKKAPD GTVIPNGYCD FCLGGSKKTG CPEDLISCAD Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%.

May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DPF1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene DPF1
Gene Accession No. P56163, Q92782
Gene Alias Baf45b; BRG1-associated factor 45B; D4, zinc and double PHD fingers family 1; double PHD fingers 1; DPF1; NEU BAF45b; NEUD4; neuro-d4; neuro-d4 homolog; neuronal d4 domain family member; zinc finger protein neuro-d4
Gene Symbols DPF1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human DPF1.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 50545, 8193
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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