Invitrogen™ DRD2 Recombinant Rabbit Monoclonal Antibody (HL1478)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA547060

Catalog No. PIMA547060

Description

Store as concentrated solution. Centrifuge briefly prior to opening vial.

The DRD2 Dopamine Receptor is involved in the neuromodulation of appetitive behaviors. DRD2 may be linked to alcoholism and other substance-use disorders. Mutations in DRD2 in mice lead to the suppression of reward behavior with morphine and to the reduction of spontaneous movements, a phenotype resembling Parkinsons disease. Three alternatively spliced isoforms have been identified. DRD2 has been reported to be expressed in various regions of the brain, as well as in aorta, artery, eye, and spinal cord. ESTs have been isolated from normal pituitary and in brain, colon, lung, pancreas, and skeletal muscle cancer libraries.

Specifications

• Antigen: DRD2
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P14416, P61168, P61169
• Gene Symbols: DRD2
• Immunogen: Recombinant protein encompassing a sequence within the N-term region of Human Dopamine Receptor D2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: HL1478
• Conjugate: Unconjugated
• Gene: DRD2
• Gene Alias: D(2) dopamine receptor; D2 receptor; D2DR; D2R; Dopamine 2 receptor; Dopamine D2 receptor; dopamine receptor 2; dopamine receptor D2; dopamine receptor D2 isoform; Drd2; Drd-2; seven transmembrane helix receptor
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 13489, 1813, 24318
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov