Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Thermo Scientific™ DSS (disuccinimidyl suberate), No-Weigh™ Format

Crosslink amines to amines with disuccinimidyl suberate composed of NHS-ester groups with a membrane-permeable, mid-length spacer for intracellular protein crosslinking.

Manufacturer:  Thermo Scientific™ A39267

 View more versions of this product

Catalog No. PIA39267

Add to cart



Thermo Scientific™ Pierce DSS, also called disuccinimidyl suberate, is noncleavable and membrane permeable crosslinker that contains an amine-reactive N-hydroxysuccinimide (NHS) ester at each end of an 8-carbon spacer arm.

  • Reactive groups: NHS ester (both ends)
  • Reactive towards: amino groups (primary amines)
  • Amine reactive sulfo-NHS ester reacts rapidly with any primary amine-containing molecule
  • Membrane-permeable, allowing for intracellular crosslinking
  • High purity, crystalline reagent can be used to create high-purity conjugates
  • Non-cleavable
  • Water-insoluble (dissolve first in DMF or DMSO); compare to BS3 (Sulfo-DSS)


Qualified for Ambient or Wet Ice
Short, 11.4 angstroms
Store desiccated at 4°C.
Chemical Labeling
NHS Ester
DMF (Dimethylformamide), DMSO (Dimethylsulfoxide)
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit