DTX2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-2179	Proteintech Group Inc 185651AP150UL	150 μL

Description

DTX2 functions as an E3 ubiquitin ligase. Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Specifications

• Antigen: DTX2
• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: Q86UW9, Q8R3P2
• Gene ID (Entrez): 113878, 304591, 74198
• Immunogen: DTX2 Fusion Protein Ag4376
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: DTX2

• Concentration: 0.19 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: deltex homolog 2 (Drosophila), Deltex2, DTX2, hDTX2, KIAA1528, Protein deltex 2, RING finger protein 58, RNF58
• Gene Symbols: Dtx2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody