DTYMK Monoclonal Antibody (C17), Invitrogen™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
FEMA550987	Invitrogen™ MA550987	200 μL
FEMA550988	Invitrogen™ MA550988	20 μL

Description

Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.

Specifications

• Antigen: DTYMK
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene Alias: AU044245; CDC8; D10Ertd203e; deoxythymidylate kinase; deoxythymidylate kinase (thymidylate kinase); dTMP kinase; DTYMK; mtmk; PP3731; Thymidylate kinase; Tmk; TMPK; TYMK; TYPK
• Gene Symbols: DTYMK
• Isotype: IgG1 κ
• Purification Method: Protein A/G
• Gene: DTYMK

• Clone: C17
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Mouse, Rat
• Gene Accession No.: P97930
• Gene ID (Entrez): 21915, 301622
• Immunogen: Recombinant Mouse DTYMK protein, Pro43-Glu190 (Accession #P97930).
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.