DTYMK Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-157-0949	Bethyl Laboratories, Inc A305652AT	20 μL

Description

The recommended shelf life for this product is 1 year from date of receipt.

Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.

Specifications

• Antigen: DTYMK
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: Thymidylate kinase; dTMP kinase; CDC8; TMPK; TYMK
• Immunogen: Between 162 and 212
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: DTYMK

• Applications: Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: P23919, P97930
• Gene ID (Entrez): 1841, 21915
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody