Dupilumab Recombinant Human Monoclonal Antibody, Invitrogen™

Human Recombinant Monoclonal Antibody

Supplier:  Thermo Scientific MA541985

Catalog No. PIMA541985

Description

Endotoxin level < 0.01EU/μg by LAL method Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.

Dupilumab with trade name Dupixent, is an FDA-approved drug for the treatment of patients aged 6 years and older with moderate-to-severe atopic dermatitis. It is a human monoclonal antibody. Dupilumab binds to the interleukin-4 receptor alpha (IL-4R alpha) subunit shared by the interleukin (IL)-4 and IL-13 receptor complexes, thereby inhibiting IL-4 and IL-13 signaling.

Specifications

• Antigen: Dupilumab
• Classification: Recombinant Monoclonal
• Conjugate: Unconjugated
• Gene Alias: Dupixent; REGN668; SAR231893
• Immunogen: Human IL4R/CD124
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid
• Target Molecule: Chemical

• Applications: ELISA, SDS-Page
• Concentration: 2.1 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Host Species: Human
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Chemical
• Product Type: Antibody
• Isotype: IgG4 κ

Safety and Handling

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