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Dynasore, Tocris Bioscience™
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Catalog No. 289750
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Non-competitive dynamin inhibitor

Dynasore is a non-competitive reversible inhibitor of dynamin 1, dynamin 2 and mitochondrial dynamin (Drp1) GTPase activity. Dynasore blocks endocytic pathways dependent on dynamin and inhibits cell spreading and migration of BSC1 cells. Dynasore attenuates motor symptoms in an animal model of Parkinson's disease and in a cellular model of Alzheimer's disease it reduces tau protein aggregation and internalization.

Chemical Identifiers

CAS 304448-55-3
Molecular Formula C18H14N2O4
Molecular Weight (g/mol) 322.32
MDL Number MFCD00292551
InChI Key NRQJUIHYFNUXFT-UHFFFAOYSA-N
Synonym dynamin inhibitor i, dynasore, n'-3,4-dihydroxybenzylidene-3-hydroxy-2-naphthohydrazide, 3-hydroxy-n'-3-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene methyl naphthalene-2-carbohydrazide, dynasore monohydrate, n'-1e-3,4-dihydroxyphenyl methylidene-3-hydroxynaphthalene-2-carbohydrazide, n'-3,4-dihydroxyphenyl methylidene-3-hydroxynaphthalene-2-carbohydrazide, 2-naphthalenecarboxylicacid, 3-hydroxy-, 2-3,4-dihydroxyphenyl methylene hydrazide
PubChem CID 6739924
IUPAC Name 3-hydroxy-N'-[(3-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]naphthalene-2-carbohydrazide
SMILES OC1=CC(=CNNC(=O)C2=CC3=CC=CC=C3C=C2O)C=CC1=O

Specifications

Quantity 50 mg
Formula Weight 322.32
Percent Purity >99%
Chemical Name or Material Dynamin Inhibitors

Safety and Handling

Recommended Storage Store at -20°C
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