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E2F1 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

$151.31

Specifications

Antigen E2F1
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Form Liquid
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-155-8393
Encompass_Preferred
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Bethyl Laboratories, Inc
A300766AT
20 μL
Each of 1 for $151.31
Only null left
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Description

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse

E2F1 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.
Specifications

Specifications

E2F1
Polyclonal
Liquid
RUO
TBS with 0.1% BSA and 0.09% sodium azide
E2F-1, RBAP1, RBBP3, RBP3
E2F1
IgG
Antigen affinity chromatography
Antibody
Western Blot
Unconjugated
Rabbit
Human
Q01094
1869
Between 387 and 437
Primary
4° C
E2F1
Videos
SDS
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Documents

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