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Tocris Bioscience™ Eact
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Catalog No. 487610
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Catalog No. Quantity
48-761-0 10 mg
48-765-0 50 mg
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Catalog No. 48-761-0 Supplier Tocris Bioscience™ Supplier No. 4876/10
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Description

Activator of Ca2+-activated Cl- channel transmembrane protein 16A (TMEM16A)

TMEM16A (ANO1) calcium-activated chloride channel (CaCC) activator (EC50 = 3 μM). Also transient receptor potential vanilloid 1 (TRPV1) channel activator (EC50 = 11.6 μM). Ca2+-independent. Displays no effect on CFTR Cl- or ENaC Na+ conductance. Stimulates submucosal gland secretion in human bronchi.

Chemical Identifiers

CAS 461000-66-8
Molecular Formula C22H24N2O5S

Specifications

Quantity 10 mg
Formula Weight 428.5
Purity >99%
Molecular Weight (g/mol) 428.503
Chemical Name or Material Eact

Safety and Handling

Recommended Storage Store at +4°C
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