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EBV Early Antigens Antibody (1108-1), Alexa Fluor™ 350, Novus Biologicals™
SDP

Catalog No. NP23416A30 Shop All R&D Systems Products
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NP23416A30 0.1 mL
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Catalog No. NP23416A30 Supplier Novus Biologicals Supplier No. NBP234516AF350
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Description

Mouse Monoclonal Antibody

EBV Early Antigens Monoclonal specifically detects EBV Early Antigens in Virus samples. It is validated for Immunocytochemistry/Immunofluorescence.

Specifications

Antigen EBV Early Antigens
Applications Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone 1108-1
Conjugate Alexa Fluor 350
Dilution Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, p40, p51, p63, p73L, TP63, Transformation-related protein 63, Tumor protein 63, Tumor protein p73-like
Host Species Mouse
Immunogen Affinity purified early antigen polypeptides from induced Raji cells precipitated with African Burkitt′s lymphoma sera
Purification Method Protein A or G purified
Quantity 0.1 mL
Primary or Secondary Primary
Test Specificity Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication.
Target Species Virus
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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